A Case of Erythroderma Secondary to Hypereosinophilia
Published: May 1, 2016 | DOI: https://doi.org/10.7860/JCDR/2016/.7770
Mohammed Shafi Abdulsalam, Hari Chandana Ghanta, Prabu Pandurangan, Maya Menon, Sheba S.K. Jacob
1. Post Graduate Student, Department of Internal Medicine, Greams Road, Apollo Main Hospital, Chennai, Tamil Nadu, India.
2. Associate Consultant Physician, Department of Internal Medicine, Greams Road, Apollo Main Hospital, Chennai, Tamil Nadu, India.
3. Consultant Haematologist, Department of Haematology, Greams Road, Apollo Main Hospital, Chennai, Tamil Nadu, India.
4. Senior Consultant Pathologist, Department of Pathology, Greams Road, Apollo Main Hospital, Chennai, Tamil Nadu, India.
5. Consultant Pathologist, Department of Pathology, Greams Road, Apollo Main Hospital, Chennai, Tamil Nadu, India.
Correspondence
Dr. Prabu Pandurangan,
Consultant Haematologist, Department of Haematology, Greams Road, Apollo Main Hospital, Chennai, Tamil Nadu, India.
E-mail: drprabu.p@gmail.com
Hypereosinophilic syndrome (HES) is a myeloproliferative disorder characterised by marked peripheral eosinophilia and end organ damage attributable to eosinophilia without secondary cause. Early recognition and treatment are essential to prevent morbidity and mortality. Cytoreduction with Steroids, Hydroxyurea and Imatinib are the main stay of treatment. Molecular studies like Fip1-like-1 fused with platelet derived growth factor receptor alpha (FIP1L1-PDGFRa) etc., are recommended in view of therapeutic implication. In this paper we report a rare case of HES developing in a lady 6 months after surgical removal of lymphangioma of spleen, which in itself is rare.
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